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1

REGULATION OF CYP3A GENE TRANSCRIPTION BY THE PREGNANE X RECEPTOR*

Goodwin, Bryan, Redinbo, Matthew R., Kliewer, Steven A.

Journal:

Annual Review of Pharmacology

Year:

2002

Language:

english

File:

PDF, 488 KB

english, 2002

2

Ghanaian national policy toward indigenous healers: The case of the Primary Health Training for Indigenous Healers (PRHETIH) program

D.M. Warren, G. Steven Bova, Mary Ann Tregoning, Mark Kliewer

Journal:

Social Science & Medicine

Year:

1982

Language:

english

File:

PDF, 1.12 MB

english, 1982

3

βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism

Xunshan Ding, Jamie Boney-Montoya, Bryn M. Owen, Angie L. Bookout, Katie Colbert Coate, David J. Mangelsdorf, Steven A. Kliewer

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 870 KB

english, 2012

4

P EROXISOME P ROLIFERATOR –A CTIVATED R ECEPTOR γ AND M ETABOLIC D ISEASE

Willson, Timothy M., Lambert, Millard H., Kliewer, Steven A.

Journal:

Annual Review of Biochemistry

Year:

2001

Language:

english

File:

PDF, 652 KB

english, 2001

5

SnapShot: Hormones of the Gastrointestinal Tract

Coate, Katie C., Kliewer, Steven A., Mangelsdorf, David J.

Journal:

Year:

2014

Language:

english

File:

PDF, 901 KB

english, 2014

6

The Nuclear Receptor DAF-12 Regulates Nutrient Metabolism and Reproductive Growth in Nematodes

Wang, Zhu, Stoltzfus, Jonathan, You, Young-jai, Ranjit, Najju, Tang, Hao, Xie, Yang, Lok, James B., Mangelsdorf, David J., Kliewer, Steven A., Mango, Susan E.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.56 MB

english, 2015

7

Assessing the stability of surface lights for use in retrievals of nocturnal atmospheric parameters

Solbrig, Jeremy E., Miller, Steven D., Zhang, Jianglong, Grasso, Lewis, Kliewer, Anton

Journal:

Atmospheric Measurement Techniques

Year:

2020

File:

PDF, 9.53 MB

2020

8

Detection of NonâGaussian Behavior Using Machine Learning Techniques: A Case Study on the Lorenz 63 Model

Goodliff, Michael, Fletcher, Steven, Kliewer, Anton, Forsythe, John, Jones, Andrew

Journal:

Journal of Geophysical Research Atmospheres

Year:

2020

File:

PDF, 16.98 MB

2020

9

ChemInform Abstract: Chemical Genomics: Functional Analysis of Orphan Nuclear Receptors in the Regulation of Bile Acid Metabolism.

Timothy M. Willson, Stacey A. Jones, John T. Moore, Steven A. Kliewer

Journal:

Year:

2001

File:

PDF, 27 KB

2001

10

Chemical genomics: Functional analysis of orphan nuclear receptors in the regulation of bile acid metabolism

Timothy M. Willson, Stacey A. Jones, John T. Moore, Steven A. Kliewer

Journal:

Medicinal Research Reviews

Year:

2001

Language:

english

File:

PDF, 216 KB

english, 2001

11

Nuclear receptors, FGFs, and the regulation of nutrient metabolism

Steven A. Kliewer, David J. Mangelsdorf

Journal:

Chemistry and Physics of Lipids

Year:

2009

Language:

english

File:

PDF, 217 KB

english, 2009

12

Use of the nuclear receptor PXR to predict drug interactions

John T. Moore, Steven A. Kliewer

Journal:

Year:

2000

Language:

english

File:

PDF, 508 KB

english, 2000

13

B-Lyl Cells: Immortal Ly-1 + B Lymphocyte Cell Lines Spontaneously Arising in Murine Splenic Cultures

Jonathan Braun, Yoar Citr, David Baltimore, Fardad Forouzanpour, Lily King, Kevin Teheranizadeh, Molly Bray, Steven Kliewer

Journal:

Immunological Reviews

Year:

1986

Language:

english

File:

PDF, 3.80 MB

english, 1986

14

Discovery of Ligands for the Nuclear Peroxisome Proliferator-activated Receptors

TIMOTHY M. WILLSON, JÜRGEN M. LEHMANN, STEVEN A. KLIEWER

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 407 KB

english, 1996

15

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

Kliewer, Steven A., Umesono, Kazuhiko, Mangelsdorf, David J., Evans, Ronald M.

Journal:

Year:

1992

File:

PDF, 636 KB

1992

16

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

Kliewer, Steven A., Umesono, Kazuhiko, Noonan, Daniel J., Heyman, Richard A., Evans, Ronald M.

Journal:

Year:

1992

File:

PDF, 601 KB

1992

17

PXR, CAR AND DRUG METABOLISM

Kliewer, Steven A., Willson, Timothy M.

Journal:

Nature Reviews Drug Discovery

Year:

2002

Language:

english

File:

PDF, 541 KB

english, 2002

18

Impact of Exposure to Community Violence on Anxiety: A Longitudinal Study of Family Social Support as a Protective Factor for Urban Children

Kamila S. White, Steven E. Bruce, Albert D. Farrell, Wendy Kliewer

Journal:

Journal of Child and Family Studies

Year:

1998

Language:

english

File:

PDF, 1.32 MB

english, 1998

19

The Structure−Activity Relationship between Peroxisome Proliferator-Activated Receptor γ Agonism and the Antihyperglycemic Activity of Thiazolidinediones

Willson, Timothy M., Cobb, Jeffery E., Cowan, David J., Wiethe, Robert W., Correa, Itzela D., Prakash, Shimoga R., Beck, Kelli D., Moore, Linda B., Kliewer, Steven A., Lehmann, Jürgen M.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 176 KB

english, 1996

20

Regulation of nutrient metabolism by nuclear receptor/FGF signaling pathways

Kliewer, Steven A, Mangelsdorf, David J

Journal:

BMC Proceedings

Year:

2012

Language:

english

File:

PDF, 161 KB

english, 2012

21

NMR Assignments and Secondary Structure of the Retinoid X Receptor α DNA-binding Domain : Evidence for the Novel C-terminal Helix

Min S. Lee, Daniel S. Sem, Steven A. Kliewer, Joan Provencal, Ronald M. Evans, Peter E. Wright

Journal:

Year:

1994

Language:

english

File:

PDF, 1.04 MB

english, 1994

22

Cloning and Characterization of Human Estrogen Receptor β Isoforms

John T. Moore, David D. McKee, Kimberly Slentz-Kesler, Linda B. Moore, Stacey A. Jones, Earnest L. Horne, Jui-Lan Su, Steven A. Kliewer, Jürgen M. Lehmann, Timothy M. Willson

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 926 KB

english, 1998

23

Fibroblast Growth Factor-21 Regulates PPARγ Activity and the Antidiabetic Actions of Thiazolidinediones

Paul A. Dutchak, Takeshi Katafuchi, Angie L. Bookout, Jang Hyun Choi, Ruth T. Yu, David J. Mangelsdorf, Steven A. Kliewer

Journal:

Year:

2012

Language:

english

File:

PDF, 1.76 MB

english, 2012

24

Inhibition of Growth Hormone Signaling by the Fasting-Induced Hormone FGF21

Takeshi Inagaki, Vicky Y. Lin, Regina Goetz, Moosa Mohammadi, David J. Mangelsdorf, Steven A. Kliewer

Journal:

Cell Metabolism

Year:

2008

Language:

english

File:

PDF, 480 KB

english, 2008

25

The Nuclear Xenobiotic Receptor CAR: Structural Determinants of Constitutive Activation and Heterodimerization

Kelly Suino, Li Peng, Ross Reynolds, Yong Li, Ji-Young Cha, Joyce J. Repa, Steven A. Kliewer, H.Eric Xu

Journal:

Year:

2004

Language:

english

File:

PDF, 2.49 MB

english, 2004

26

Crystallographic Identification and Functional Characterization of Phospholipids as Ligands for the Orphan Nuclear Receptor Steroidogenic Factor-1

Yong Li, Mihwa Choi, Greg Cavey, Jennifer Daugherty, Kelly Suino, Amanda Kovach, Nathan C. Bingham, Steven A. Kliewer, H.Eric Xu

Journal:

Year:

2005

Language:

english

File:

PDF, 1.16 MB

english, 2005

27

Pregnane X receptor: Predicting and preventing drug interactions

Steven A. Kliewer

Journal:

Thrombosis Research

Year:

2005

Language:

english

File:

PDF, 81 KB

english, 2005

28

Anthrax mounts a nuclear attack on glucocorticoid signaling

Steven A Kliewer

Journal:

Trends in Pharmacological Sciences

Year:

2003

Language:

english

File:

PDF, 56 KB

english, 2003

29

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

Steven A Kliewer, John T Moore, Laura Wade, Jeff L Staudinger, Michael A Watson, Stacey A Jones, David D McKee, Beverly B Oliver, Timothy M Willson, Rolf H Zetterström, Thomas Perlmann, Jürgen M Lehma

Journal:

Year:

1998

Language:

english

File:

PDF, 2.29 MB

english, 1998

30

The nuclear receptor PPARγ-bigger than fat

Steven A Kliewer, Timothy M Willson

Journal:

Current Opinion in Genetics & Development

Year:

1998

Language:

english

File:

PDF, 809 KB

english, 1998

31

Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors

Robert T. Gampe Jr., Valerie G. Montana, Millard H. Lambert, Aaron B. Miller, Randy K. Bledsoe, Michael V. Milburn, Steven A. Kliewer, Timothy M. Willson, H.Eric Xu

Journal:

Year:

2000

Language:

english

File:

PDF, 754 KB

english, 2000

32

Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

H.Eric Xu, Millard H Lambert, Valerie G Montana, Derek J Parks, Steven G Blanchard, Peter J Brown, Daniel D Sternbach, Jürgen M Lehmann, G.Bruce Wisely, Timothy M Willson, Steven A Kliewer, Michael V

Journal:

Year:

1999

Language:

english

File:

PDF, 333 KB

english, 1999

33

N -(2-Benzoylphenyl)- l -tyrosine PPARγ Agonists. 1. Discovery of a Novel Series of Potent Antihyperglycemic and Antihyperlipidemic Agents

Henke, Brad R., Blanchard, Steven G., Brackeen, Marcus F., Brown, Kathleen K., Cobb, Jeff E., Collins, Jon L., Harrington,, W. Wallace, Hashim, Mir A., Hull-Ryde, Emily A., Kaldor, Istvan, Kliewer, St

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 436 KB

english, 1998

34

2.1 Å Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin †,‡

Watkins, Ryan E., Maglich, Jodi M., Moore, Linda B., Wisely, G. Bruce, Noble, Schroeder M., Davis-Searles, Paula R., Lambert, Mill H., Kliewer, Steven A., Redinbo, Matthew R.

Journal:

Year:

2003

Language:

english

File:

PDF, 428 KB

english, 2003

35

Chronic Diarrhea Due to Excessive Bile Acid Synthesis and Not Defective Ileal Transport: A New Syndrome of Defective Fibroblast Growth Factor 19 Release

Alan F. Hofmann, David J. Mangelsdorf, Steven A. Kliewer

Journal:

Clinical Gastroenterology and Hepatology

Year:

2009

Language:

english

File:

PDF, 464 KB

english, 2009

36

A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

David J. Mangelsdorf, Kazuhiko Umesono, Steven A. Kliewer, Uwe Borgmeyer, Estelita S. Ong, Ronald M. Evans

Journal:

Year:

1991

Language:

english

File:

PDF, 1.83 MB

english, 1991

37

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

Roland Schüle, Pundl Rangarajan, Steven Kliewer, Lynn J. Ransone, Jack Bolado, Na Yang, Inder M. Verma, Ronald M. Evans

Journal:

Year:

1990

Language:

english

File:

PDF, 1.28 MB

english, 1990

38

Effects of troglitazone and metformin on glucose and lipid metabolism: Alterations of two distinct molecular pathways

James M Lenhard, Steven A Kliewer, Mark A Paulik, Kelli D Plunket, Jurgen M Lehmann, James E Weiel

Journal:

Biochemical Pharmacology

Year:

1997

Language:

english

File:

PDF, 970 KB

english, 1997

39

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

Bookout, Angie L, de Groot, Marleen H M, Owen, Bryn M, Lee, Syann, Gautron, Laurent, Lawrence, Heather L, Ding, Xunshan, Elmquist, Joel K, Takahashi, Joseph S, Mangelsdorf, David J, Kliewer, Steven A

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 1.68 MB

english, 2013

40

FGF21 contributes to neuroendocrine control of female reproduction

Owen, Bryn M, Bookout, Angie L, Ding, Xunshan, Lin, Vicky Y, Atkin, Stan D, Gautron, Laurent, Kliewer, Steven A, Mangelsdorf, David J

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 527 KB

english, 2013

41

Fatty Acids and Eicosanoids Regulate Gene Expression through Direct Interactions with Peroxisome Proliferator-Activated Receptors α and γ

Steven A. Kliewer, Scott S. Sundseth, Stacey A. Jones, Peter J. Brown, G. Bruce Wisely, Cecilia S. Koble, Pallavi Devchand, Walter Wahli, Timothy M. Willson, James M. Lenhard and Jurgen M. Lehmann

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 968 KB

english, 1997

42

Activation of the Orphan Receptor RIP14 by Retinoids

Ann Marie Zavacki, Jurgen M. Lehmann, Wongi Seol, Timothy M. Willson, Steven A. Kliewer and David D. Moore

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.40 MB

english, 1997

43

Structural Requirements of Ligands for the Oxysterol Liver X Receptors LXR α and LXRβ

Bethany A. Janowski, Michael J. Grogan, Stacey A. Jones, G. Bruce Wisely, Steven A. Kliewer, Elias J. Corey and David J. Mangelsdorf

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.42 MB

english, 1999

44

Regulation of metabolism by a neuroendocrine FGF signaling pathway

Mangelsdorf, David J, Kliewer, Steven A

Journal:

Cancer & Metabolism

Year:

2014

Language:

english

File:

PDF, 85 KB

english, 2014

45

FGF21 Acts Centrally to Induce Sympathetic Nerve Activity, Energy Expenditure, and Weight Loss

Owen, Bryn M., Ding, Xunshan, Morgan, Donald A., Coate, Katie Colbert, Bookout, Angie L., Rahmouni, Kamal, Kliewer, Steven A., Mangelsdorf, David J.

Journal:

Cell Metabolism

Year:

2014

Language:

english

File:

PDF, 796 KB

english, 2014

46

Crystal Structure of the Pregnane X Receptor-Estradiol Complex Provides Insights into Endobiotic Recognition

Xue, Yu, Moore, Linda B., Orans, Jillian, Peng, Li, Bencharit, Sompop, Kliewer, Steven A., Redinbo, Matthew R.

Journal:

Molecular Endocrinology

Year:

2007

Language:

english

File:

PDF, 827 KB

english, 2007

47

Nuclear Receptor LRH-1 Induces the Reproductive Neuropeptide Kisspeptin in the Hypothalamus

Atkin, Stan D., Owen, Bryn M., Bookout, Angie L., Cravo, Roberta M., Lee, Charlotte, Elias, Carol F., Elmquist, Joel K., Kliewer, Steven A., Mangelsdorf, David J.

Journal:

Molecular Endocrinology

Year:

2013

Language:

english

File:

PDF, 1.67 MB

english, 2013

48

Comprehensive Messenger Ribonucleic Acid Profiling Reveals That Peroxisome Proliferator-Activated Receptor γ Activation Has Coordinate Effects on Gene Expression in Multiple Insulin-Sensitive Tissues

Way, James M., Harrington, W. Wallace, Brown, Kathleen K., Gottschalk, William K., Sundseth, Scott S., Mansfield, Traci A., Ramachandran, Ravi K., Willson, Timothy M., Kliewer, Steven A.

Journal:

Year:

2001

Language:

english

File:

PDF, 1.11 MB

english, 2001

49

Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21

Owen, Bryn M., Mangelsdorf, David J., Kliewer, Steven A.

Journal:

Trends in Endocrinology & Metabolism

Year:

2015

Language:

english

File:

PDF, 566 KB

english, 2015

50

Retinoic Acid is a Negative Regulator of AP-1-Responsive Genes

Roland Schule, Pundi Rangarajan, Na Yang, Steven Kliewer, Lynn J. Ransone, Jack Bolado, Inder M. Verma and Ronald M. Evans

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 892 KB

english, 1991